Lacto-N-neotetraos_SYNAURA_SYNAURA,HMO supplier,HMOs,Human Milk Oligosaccharides,2'-FL,LNnT,3'-SL, infant formula ingredient, nutritional raw material

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Lactose-N-neotetraose（LNnT）

Human Milk Oligosaccharides（HMOs）

Human milk oligosaccharides (HMOs) are the third largest solid component in breast milk and the largest active nutrient. Currently, more than 200 HMOs have been identified. Since oligosaccharides chains can be fucosylated or sialylated, they are usually divided into three categories：

（a）Fucosylated neutral HMO(35-50%)

（b）Nonfucosylated neutral HMO (42-55%)

（c）Sialylated HMO (12-14%)

Representative compounds of Nonfucosylated neutral HMO——Lactose-N-neotetraose（LNnT）

Neutral non-fucosylated HMOs are the core skeletons of various complex HMO structures.

It is ubiquitous in almost all breast milk and is not affected by the type of breast milk.

The prebiotic function of specific probiotics with 2'-FL as clinical research subjects is more pronounced, and often combined.

SYNAURA HMOs Product Advantages

First Chinese company with dual certification from China and the U.S.

——China's first 2'-fucosyllactose (2-FL) product approved by both the Chinese National Health Commission and the U.S. FDA GRAS certification

Global leading patents layout

——A total of 50+ domestic and international patent applications, with 30+ patents granted to date. Patents

covering HMO strain development, process optimization, testing, and application, establish an independent

original research and development patent system.

Reference

1. Rousseaux, A., et al. (2021). Human Milk Oligosaccharides: Their Effects on the Host and Their Potential as Therapeutic Agents. Frontiers in Immunology, 12, Article 801911.

2. Lacto-N-neotetraose. PubChem; National Center for Biotechnology Information. https://pubchem.ncbi.nlm.nih.gov/compound/121853 (accessed 2025-09-01).

3. Kobata, A. (2010). Structures and application of oligosaccharides in human milk. Proceedings of the Japan Academy, Series B, 86(7), 731–747.

4. Thurl, S., et al. (2017). Variation of human milk oligosaccharides in relation to milk groups and lactational periods. British Journal of Nutrition, 104(9), 1261–1271.

5. Elison, E., et al. (2016). Oral supplementation of healthy adults with 2′-O-fucosyllactose and lacto-N-neotetraose is well tolerated and shifts the intestinal microbiota. The American Journal of Clinical Nutrition, 104(3), 1001–1009.

6. *The certification results are sourced from third-party organizations, including the《2025 Certificate of Conformity Verification》and the《2023 2'-FL Chemical Structural Equivalence Experiment》; the analytical data is sourced from the GRAS application data submitted by various companies.

China Headquarters

Xiaowei Zhang:+86-13910088419(WeChat)

Wenqiang Wang:+86-13811202192(WeChat)

GLOBAL OFFICE

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Xinhui LI: +86-18241587387(WeChat)

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